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immunoglobulin-G2 (IgG2)
IgG2 is a weak binder of complement.
Laboratory:
- IgG2 in serum
Related
complement-fixing antibody
IgG2 in serum
General
immunoglobulin-G (IgG, Cuvitru)
Properties
SIZE: MW = 150 kD
COMPARTMENT: plasma
SECRETED-BY: plasma cell
SUBUNITS: Ig-gamma (2)
MOTIF: Ig heavy chain variable region
NAME: Ig heavy chain variable region
heavy chain constant region-1
MOTIF: cysteine residue {CH1.SITE1}
MODIFICATION: cysteine residue {CH1.SITE2}
cysteine residue {CH1.SITE2}
MODIFICATION: cysteine residue {CH1.SITE1}
cysteine residue {C-TO-CH1}
MODIFICATION: cysteine residue {C-TO-CL}
hinge region
MOTIF: cysteine residue {HINGE1}
MODIFICATION: cysteine residue {HINGE1}
cysteine residue {HINGE2}
MODIFICATION: cysteine residue {HINGE2}
heavy chain constant region-2
MOTIF: cysteine residue {CH2.SITE1}
MODIFICATION: cysteine residue {CH2.SITE2}
cysteine residue {CH2.SITE2}
MODIFICATION: cysteine residue {CH2.SITE1}
heavy chain constant region-3
MOTIF: cysteine residue {CH3.SITE1}
MODIFICATION: cysteine residue {CH3.SITE2}
cysteine residue {CH3.SITE2}
MODIFICATION: cysteine residue {CH3.SITE1}
immunoglobulin light chain (2)
MOTIF: Ig light chain variable region
NAME: Ig light chain variable region
light chain constant region
MOTIF: cysteine residue {CLSITE1}
MODIFICATION: cysteine residue {CL.SITE2}
cysteine residue {CL.SITE2}
MODIFICATION: cysteine residue {CL.SITE1}
cysteine residue {C-TO-CL}
MODIFICATION: cysteine residue {C-TO-CH1}
References
Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998
Components
immunoglobulin gamma chain (Ig-gamma)
immunoglobulin light chain