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IFNL3 (IL28B) variation rs12979860

Indications: - hepatitis C genotype 1 infection Clinical significance: - IFNL3 (IL28B) variation (rs12979860) is the strongest baseline predictor of response to PEG-interferon-alpha- containing regimens in HCV genotype 1 patients [1]

General

gene mutation testing; gene mutation analysis

References

  1. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline information for boceprevir, peginterferon alfa-2a, peginterferon alfa-2b, ribavirin, telaprevir and IFNL3. https://www.pharmgkb.org/guideline/PA166110235