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ICU-acquired weakness

Clinical manifestations: - muscle weakness - proximal & distal symmetric flaccid weakness - sparing of cranial nerves - failure to weaning from ventilation is often 1st sign * diagnosis of exclusion Special laboratory: - Medical Research Council muscle scale 1st step in evalutating ICU-acquired weakness [1] (rarely used [1]) Management: - aggressive management of critical illness - early mobilization - management of hyperglycemia [1]

Related

critical illness weakness; critical illness neuromyopathy

General

critical illness syndrome

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 18, 19 American College of Physicians, Philadelphia 2018, 2022
  2. Fan E, Cheek F, Chlan L et al An official American Thoracic Society Clinical Practice guideline: the diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med. 2014 Dec 15;190(12):1437-46. PMID: 25496103