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hypoactive sexual desire disorder (HSDD); sexual interest/arousal disorder

Low sexual desire in a woman that causes personal distress Etiology: - menopause Epidemiology: - prevalence 12-19% [2] - increased prevalence in surgically postmenopausal women (26% vs 14%) History: - screen for depression Complications: - marked personal distress &/or interpersonal difficulty Management: - couples sex therapy may be beneficial [2] - treatment of underlying illness - treatment of depression - elimination of unnecessary medications - there is no FDA-approved medication for treatment of HSDD [2] - transdermal testosterone - approved in Europe for postmenopausal women who experience HSDD as a result of bilateral oophorectomy [3] - not recommended in U.S. by Endocrine Society [4]

General

sexual dysfunction

References

  1. Leiblum SR et al, Hypoactive sexual desire disorder in postmenopausal women: US results from the Women's International Study of Health and Sexuality (WISHeS) Menopause 2006; 13:46 - Kinsberg SA. Prevalence of hypoactive sexual desire disorder in postmenopausal women: Results fromm the WISHeS trial Menopause 2006; 13:10
  2. Medical Knowledge Self Assessment Program (MKSAP) 16, 17. American College of Physicians, Philadelphia 2012, 2015
  3. Nappi RE, Martini E, Terreno E et al Management of hypoactive sexual desire disorder in women: current and emerging therapies. Int J Womens Health. 2010 Aug 9;2:167-75. PMID: 21072309
  4. Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
  5. Panay N1, Al-Azzawi F, Bouchard C et al Testosterone treatment of HSDD in naturally menopausal women: the ADORE study. Climacteric. 2010 Apr;13(2):121-31 PMID: 20166859