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hyperplastic polyp

Pathology: 1) distinct from serrated polyps & adenomatous polyps 2) pathologic distinction between hyperplastic polyps sessile serrated adenomas is not reliable in clinical practice & can be difficult, even for experts [4] 3) no increased risk of proximal colon cancer with distal hyperplastic polyps [2] Management: - malignant potential similar to general population* - follow-up colonoscopy in 10 years [5]

Related

serrated polyposis syndrome; hyperplastic polyposis syndrome

General

colorectal polyp

References

  1. Journal Watch 21(19):151, 2001 Hawkins & Ward J Natl Cancer Inst 93:1307, 2001
  2. Lin OS, Schembre DB, McCormick SE, Gluck M, Patterson DJ, Jiranek GC, Soon MS, Kozarek RA. Risk of proximal colorectal neoplasia among asymptomatic patients with distal hyperplastic polyps. Am J Med. 2005 Oct;118(10):1113-9. PMID: 16194642
  3. Pathology Outlines Colon tumor, Polyps, Adenoma-carcinoma sequence of colon http://www.pathologyoutlines.com/topic/colontumoradenomacarcinoma.html
  4. Schreiner MA et al. Proximal and large hyperplastic and nondysplastic serrated polyps detected by colonoscopy are associated with neoplasia. Gastroenterology 2010 Nov; 139:1497. PMID: 20633561 - Hiraoka S et al. The presence of large serrated polyps increases risk for colorectal cancer. Gastroenterology 2010 Nov; 139:1503, 1510. - Terdiman JP and McQuaid KR. Surveillance guidelines should be updated to recognize the importance of serrated polyps. Gastroenterology 2010 Nov; 139:1444. PMID: 20875785
  5. Medical Knowledge Self Assessment Program (MKSAP) 17, 18. American College of Physicians, Philadelphia 2015, 2018.