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hypericin
Psoralen-like compound that uses visible, rather than UV radiation.
Component of St. John's Wort
Dosage: 900-3600 mg PO [3]
Adverse effects:
- phototoxicity (cataracts in the presence of sunlight) [3]
Mechanism of action:
1) prevents replication of encapsulated viruses [3]
2) some anti-inflammatory activity
- inhibits releas of leukotrienes
Interactions
drug interactions
General
antiviral agent
enzyme inhibitor
oral dermatologic agent
Properties
INHIBITS: protein kinase C
casein kinase 2
:ENGLISH weak inhibition
MAP kinase
:ENGLISH weak inhibition
SIZE: MW = 505 GRAMS/MOLE
Database Correlations
PUBCHEM correlations
References
- Hypericin, Hypericum perforatum [H1042]
http://www.agscientific.com/Item/H1042.htm
- hypericin Facts Sheet
http://hypericin.noneto.com/
- Hypericin- A Napthodianthrone from Hypericum perforatum
Amrit Pal Singh, MD (Alternative Medicine)
http://www.siu.edu/~ebl/leaflets/article.htm