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carotenemia

Etiology: - excessive intake of carrots or other sources of carotene - yellow & green vegetables - citrus fruits - hypothyroidism - diabetes mellitus - hepatic diseases - anorexia nervosa - renal diseases Epidemiology: - most common in children Pathology: - thyroxine enhances conversion of beta-carotene to vitamin A, thus the association with hypothyroidism Clinical manifestations: - yellow discoloration of the skin - the sclera & oral cavity are unaffected - the liver & spleen are normal Laboratory: - serum carotene is elevated - serum bilirubin is normal Differential diagnosis: - hyperbilirubinemia, jaundice Complications: - amenorrhea may be associated with carotenemia Management: - generally benign condition - decrease intake of carotene-containing foods

General

sign/symptom

References

  1. Medscape: Carotenemia http://emedicine.medscape.com/article/1104368-overview