Search
hyper-IgM immunodeficiency syndrome type 5 (HIGM5)
Pathology:
- absence of Ig class switch recombination at a DNA precleavage step
Genetics:
- associated with defects in UNG
Laboratory:
- normal or elevated serum IgM levels
- absence of serum IgG, serum IgA, &serum IgE
General
hyper-IgM immunodeficiency syndrome (HIGM)
Database Correlations
OMIM 608106
References
OMIM :accession 608106