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hydroxyproline in body fluid

Indications: - assessment bone resorption (urine) - acromegaly - hyperthyroidism - hyperparathyroidism - Paget's disease of bone - rickets, osteomalacia - bone fracture - bony metastases - osteoporosis - sarcoidosis - severe burns - acute osteomyelitis - congenital hypophosphatasia - fibrous dysplasia - growth spurts Reference interval: - adult male: 9-73 mg/day (urine) - adult female: 7-49 mg/day Clinical significance: - measure of collagen turnover (urine) Increases: - acromegaly - hyperthyroidism - hyperparathyroidism - Paget's disease of bone - rickets, osteomalacia - bone fracture - bony metastases - osteoporosis - sarcoidosis - severe burns - acute osteomyelitis - congenital hypophosphatasia - fibrous dysplasia - growth spurts Decreases: - hypopituitarism - hypothyroidism - hypoparathyroidism - malnutrition - muscular dystrophy

Related

4-hydroxyproline

Specific

hydroxyproline in amniotic fluid hydroxyproline in blood hydroxyproline in CSF hydroxyproline in urine hydroxyproline in vitreous fluid

General

general chemistry test

References

  1. Clinical Guide to Laboratory Tests, 4th edition, HB Wu ed, WB Saunders, Philadelphia, 2006