checkpoint protein HUS1

Function: 1) component of the 9-1-1 cell-cycle checkpoint response complex 2) does not interact with RAD17 Compartment: - nucleus, cytoplasm - in discrete nuclear foci upon DNA damage - localized also in cytoplasm - DNA damage induces its nuclear translocation - shuttles between the nucleus & the cytoplasm Expression: ubiquitous

Properties

SIZE: MW = 32 kD entity length = 280 aa COMPARTMENT: cytoplasm cell nucleus

Database Correlations

OMIM 603760 UniProt O60921 Pfam PF04005

References

UniProt :accession O60921