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Human Leukocyte Antigen (HLA) Class I serotyping

Indications: - specific HLA-B alleles associated with drug hypersensitivity reactions a) HLA-B*5701 b) HLA-B*1502 (HLA-B75) (carbamazepine) c) HLA-B*5801 (allopurinol) - lymphoma [4] Epidemiology: - seems Hans Chinese & persons of Thai descent at risk

Related

HLA-A+B+C Ab in serum MHC class I antigen

Specific

HLA-A29 HLA-B phenotyping

General

Human Leukocyte Antigen (HLA) testing

References

  1. Prescriber's Letter 15(2): 2008 Labs for HLA (Human Leukocyte Antigen) Testing Detail-Document#: 240211 (subscription needed) http://www.prescribersletter.com - Prescriber's Letter 16(1): 2009 Labs for HLA (Human Leukocyte Antigen) Testing Detail-Document#: 250109 (subscription needed) http://www.prescribersletter.com
  2. Khanna D et al 2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia Arthritis Care & Research, 64(10):1431-1446, October 2012 PMID: 23024028 http://onlinelibrary.wiley.com/doi/10.1002/acr.21772/abstract
  3. Labs that perform HLA testing American Red Cross, Philadelphia, PA (215) 451-4131 - Blood Systems Laboratories Histocompatibility Testing Services Tempe, AZ (866) 342-4275 http://www.bloodsystemslaboratories.org - Calgary Laboratory Services-Tissue Typing Laboratory Calgary, Alberta (Canada) (403) 770-3652 - City of Hope National Medical Center Histocompatibility Laboratory, Duarte, CA (626) 256-8621 - The Histogenetics Laboratory, Inc., Ossining, NY (914) 762-0300 http://www.histogenetics.com - Kashi Clinical Laboratories, Beaverton, OR (888) 732-4018 - Laboratory Corporation of America Holdings, Burlington, NC (800) 533-1037 http://www.labcorp.com - METIC Immunogenetics Consultants, Inc., Los Angeles, CA (323) 441-1111 http://www.metic.com - Quest Diagnostics Nichols Institute Chantilly, VA (800) 336-3718 http://www.questdiagnostics.com - Specialty Laboratories, Valencia, CA (800) 421-4449 http://www.specialtylabs.com - The Toronto Hospital Toronto, ON (Canada) (416) 340-4995 - Vancouver Acute, Laboratory Reception, Vancouver, BC (Canada) (604) 875-4111 http://www.vch.ca
  4. Deprecated Reference