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human herpesvirus type 7 (HHV-7)
Pathology:
- virus latent in T-cells
- HHV7 may affect metabolism of beta-amyloid precursor protein in brain [2]
Clinical manifestations:
- generally asymptomatic
- 6th disease in children
Laboratory:
- Herpes virus 7 serology
- Herpes virus 7 IgM in serum
- Herpes virus 7 IgG in serum
- Herpes virus 7 DNA
Related
Herpes virus 7 DNA
General
herpesviridae
Properties
KINGDOM: virus
GENOME-TYPE: deoxyribonucleic acid (DNA)
DOUBLE-STRANDED
GENOME-SIZE: 120-200 kB
ENVELOPE: PRESENT
CAPSID-SYMMETRY: ICOSAHEDRAL
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, 17, 18.
American College of Physicians, Philadelphia 1998, 2015, 2018.
- Readhead B, Haure-Mirande JV, Funk CC et al
Multiscale Analysis of Independent Alzheimer's Cohorts Finds
Disruption of Molecular, Genetic, and Clinical Networks by Human
Herpesvirus.
Neuron. June 2018.
PMID: 29937276
https://www.cell.com/neuron/fulltext/S0896-6273(18)30421-5