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homeodomain
The homeobox is a protein domain of 60 amino acid residues, 1st identified in Drosophila homeotic & segmentation proteins.
The homeobox domain is extremely well conserved in many other animals, including vertebrates. It binds DNA through a helix-turn-helix. Some proteins which contain a homeobox domain play an important role in development. Most of these proteins are sequence specific DNA-binding transcription factors.
Most proteins which contain a homeobox domain can be classified on the basis of sequence, into 1 of 3 subfamilies:
1) engrailed
2) antennapedia
3) paired
Related
DNA motif
Specific
homeobox antennapedia type
homeobox engrailed type
homeobox tale type
paired box
POU domain
General
helix-loop-helix (HLH)
DNA-binding motif
domain
References
prosite :accession PS00027