HMG CoA reductase gene

5q13.3-q14

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: HMG CoA reductase MOTIF: sterol regulatory element-1 (SRE-1) SITE: -290 FOR-BINDING-OF: sterol regulatory element-binding protein 1 MOTIF-SEQUENCE: CACGCCAC nuclear factor-1 [NF1] site NAME: nuclear factor-1 [NF1] site SITE: -180 NUCLEOTIDE-SEQUENCE: consensus consensus CpG island {promoter region} transcriptional start site (3) exon intron transcriptional termination site

References

- Vallett SM et al A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene. J Biol Chem. 1996 May 24;271(21):12247-53. PMID: 8647822