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Human Melanoma Black (HMB)-45 Ag in tissue

Indications: - evaluation of melanoma Clinical significance: - monoclonal antibody recognizing HMB45 Ag identifies melanosomal glycoprotein gp100 (Pmel17)

Related

melanocyte protein Pmel 17; Silver locus protein homolog; melanocyte lineage-specific antigen GP100; melanoma-associated ME20 antigen; ME20-M; ME20M; contains: ME20-S; secreted melanoma-associated ME20 antigen; ME20S; 95 kD melanocyte-specific secreted glycoprotein (SILV, D12S53E, PMEL17)

General

antigen in specimen/tissue

References

  1. Loinc
  2. Pernick N PathologyOutlines. Stains: HMB45 http://www.pathologyoutlines.com/topic/stainshmb45.html
  3. Gown AM, Vogel AM, Hoak D, Gough F, McNutt MA. Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. Am J Pathol. 1986 May;123(2):195-203. PMID: 3518473 Free PMC Article