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HLA-B*5701 allele

Indications: - HIV1 - assess risk of hypersensitivity to abacavir Clinical significance: - hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele

Related

HLA B*5701

General

HLA-B genotyping

References

  1. Quest Diagnostics: HLA-B*5701 Typing http://www.questdiagnostics.com/hcp/intguide/jsp/showintguidepage.jsp?fn=TH_HLA_B_5701.htm
  2. LabCorp: HLA-B*5701 Genotyping Association With Abacavir Hypersensitivity https://www.labcorp.com/wps/wcm/connect/c2669d004a162e379a96ff90b80e7bff/L1148-0208-5.pdf
  3. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline information for abacavir and HLA-B. https://www.pharmgkb.org/guideline/PA166104997
  4. ARUP consult: HLA-B*57:01 for Abacavir Sensitivity https://arupconsult.com/ati/hla-b5701-abacavir-sensitivity