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HIV1/HIV2 Ab differentiation assay

Indications: - positive HIV 1+2 Ab & HIV1 p24 Ag in serum (screening test) Clinical significance: - distinguishes HIV1 from HIV2 or suggests false positive screening test - positive HIV 1+2 Ab & HIV1 p24 Ag in serum - if negative differentiation assay, suggests HIV1 p24 Ag or false positive screening test for HIV1 [1] - a negative HIV1 nucleic acid amplification test confirms a false positive screening test for HIV1 - a positive HIV nucleic acid amplification test confirms acute HIV1 infection* * MKSAP20 [1] does not seem to acknowlege the difference between HIV1 nucleic acid amplification & HIV nucleic acid amplification testing whereas OpenEvidence does

General

HIV laboratory testing

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015 - Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025