human immunodeficiency virus-1 selections

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human immunodeficiency virus-1 (HIV-1)

see HIV1 infection Pathology: - RNA virus encoding a reverse transcriptase, with subsequent insertion of nascent DNA into cellular genome, thus causing latent & persistent infection. Genetics: - new subtype, Group M, subtype L - highly virulent subtype B (VB)* [2] - HIV1 RNA levels 0.5-0.7 log10 higher than non-VB HIV1 [2] * virulence established by HIV1 RNA levels within 6-24 months of a first positive test & rate of CD4 count decline

CD4 T lymphocyte deficiency disorder (HIV-negative AIDS) HIV1 infection; human immunodeficiency virus-1 infection

Specific

HIV infection during pregnancy

General

human immunodeficiency virus (HIV)

Properties

KINGDOM: virus GENOME-TYPE: ribonucleic acid

References

Yamaguchi J, McArthur C; Vallari A et al Complete genome sequence of CG-0018a-01 establishes HIV-1 subtype L. J Acquir Immune Defic Syndr. 2019 Nov 6 PMID: 31693506 https://journals.lww.com/jaids/Abstract/publishahead/Complete_genome_sequence_of_CG_0018a_01.96307.aspx#pdf-link
Wymant C, Bezemer D, Blanquart F et al. A highly virulent variant of HIV-1 circulating in the Netherlands. Science 2022 Feb 3; 375:540 PMID: 35113714 https://www.science.org/doi/10.1126/science.abk1688