histone deacetylase activity (GO:0004407)

Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.

Specific

histone deacetylase activity (H3-K14 specific) (GO:0031078) histone deacetylase activity (H3-K4 specific) (GO:1990162) histone deacetylase activity (H3-K9 specific) (GO:0032129) histone deacetylase activity (H4-K16 specific) (GO:0034739) NAD-dependent histone deacetylase activity (GO:0017136) NAD-independent histone deacetylase activity (GO:0045129)

General

protein deacetylase activity (GO:0033558) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)

References

gene ontology: GO:0004407 PMID: 9893272