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histone antibody in serum
Indications:
- present in drug-induced lupus
- not as frequent in idiopathic systemic lupus erythematosus
Clinical significance:
- 95% sensitivity for drug-induced lupus
- poor specificity
Specimen: serum
Storage: store at -20 C.
Method: solid phase EIA
Interferences:
- no chemical interferences or in vivo effects known
Related
anti-histone antibody
drug-induced lupus erythematosus
Specific
anti-histone H2a+H2b antibody in serum
histone antibody in serum qualitative
histone antibody in serum quantitative
histone IgG in serum
General
histone antibody in body fluid
References
Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,
W.B. Saunders, 1995