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histone acetyltransferase
Function:
- acetylation of histones plays a role in epigenetic modification of chromatin & regulation of gene expression
- facilitates epigenetic modifications that differ between identical twins
Related
bifunctional protein NCOAT; meningioma-expressed antigen 5; nuclear cytoplasmic O-GlcNAcase & acetyltransferase; includes: protein O-GlcNAcase; glycoside hydrolase O-GlcNAcase; hexosaminidase C; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; O-GlcNAcase; OGA; includes: histone acetyltransferase; HAT (MGEA5, HEXC, KIAA0679, MEA5)
histone acetyltransferase complex
histone acetyltransferase MYST3; MYST protein 3; MOZ, YBF2/SAS3, SAS2 & TIP60 protein 3; Runt-related transcription factor-binding protein 2; monocytic leukemia zinc finger protein; zinc finger protein 220 (MYST3, MOZ, RUNXBP2, ZNF220, KAT6A)
Specific
circadian locomoter output cycles kaput protein; hCLOCK; class E basic helix-loop-helix protein 8; bHLHe8 (CLOCK, BHLHE8, KIAA0334)
CREB-binding protein; CBP transcriptional coactivator (CREBBP, CBP)
general control of amino acid synthesis protein 5-like 2; histone acetyltransferase GCN5; hsGCN5; STAF97 (GCN5L2, GCN5, HGCN5, KAT2A)
histone acetyltransferase KAT7; histone acetyltransferase binding to ORC1; lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 & TIP60 protein 2; MYST-2 (KAT7, HBO1, HBOa, MYST2)
histone acetyltransferase MYST1; MYST protein 1; YBF2/SAS3; SAS2 & TIP60 protein 1; hMOF (MYST1, KAT8, MOF, PP7073)
histone acetyltransferase MYST4; MYST-4; histone acetyltransferase MORF; histone acetyltransferase MOZ2; MOZ, YBF2/SAS3, SAS2 & TIP60 protein 4; monocytic leukemia zinc finger protein-related factor (MYST4, KIAA0383, MORF, MOZ2, KAT6B)
histone acetyltransferase PCAF; histone acetylase PCAF; P300/CBP-associated factor; P/CAF (PCAF, KAT2B)
PCAF complex; coactivator for p53/TP53-dependent transcriptional activation; PCAF histone acetylase complex
General
acetyltransferase
Properties
MOTIF: active site
References
- Geriatric Review Syllabus, 11th edition (GRS11)
Harper GM, Lyons WL, Potter JF (eds)
American Geriatrics Society, 2022