histone acetyltransferase complex

Function: - acetylation of histones, including histone H4 at Lys-16, implicated in the formation of higher-order chromatin structure Structure: - subunits include: - at least MOF/MYST1, MSL1/hampin, MSL2L1 & MSL3L1

Specific

histone acetylation (HAT) complex SAGA histone acetyltransferase complex type B NuA4 histone acetyltransferase (HAT) complex

Properties

SUBUNITS: DET1 homolog COMPARTMENT: cell nucleus DET1- & DDB1-associated protein 1 FORM: DET1- & DDB1-associated protein 1 DNA damage-binding protein 1 COMPARTMENT: cytoplasm cell nucleus MOTIF: CDT1 interaction {1-768} MOTIF: Thr phosphorylation site {T8} CUL4A interaction {391-709} Ser phosphorylation site {S757} Ser phosphorylation site {S766} CDT1/CUL4A interaction {771-1140}

References

UniProt :accession O75081

Components

DET1 homolog (De-etiolated-1 homolog, DET1) DET1- & DDB1-associated protein 1 (placenta cross-immune reaction antigen 1, PCIA-1, DDA1, C19orf58, PCIA1) DNA damage-binding protein 1; damage-specific DNA-binding protein 1; UV-damaged DNA-binding factor; DDB p127 subunit; DNA damage-binding protein a; DDBa; UV-damaged DNA-binding protein 1; UV-DDB 1; Xeroderma pigmentosum group E-complementing protein; XPCe; XPE-binding factor; XPE-BF; HBV X-associated protein 1; XAP-1 (DDB1, XAP1)