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hexagonal phospholipid neutralization test

Indications: - antiphospholipid antibody syndrome Clinical significance: - laboratory assay for antiphospholipid antibody (lupus anticoagulant) - useful even when patient is anticoagulated with heparin or warfarin Interferences: - elevated serum C-reactive protein interferes qith PTT-based hexagonal phase phospholipid neutralization assay [3]

Related

lupus anticoagulant

General

lupus anticoagulant in plasma

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
  2. Hexagonal Phospholipid Neutral Laboratory Test Directory ARUP: 30064 - Panel of 12 tests Laboratory Test Directory ARUP: 30181 - Panel of 16 tests Laboratory Test Directory ARUP: 30268 - Panel of 16 tests Laboratory Test Directory ARUP: 2003222
  3. Reyes Gil M, Barouqa M, Szymanski J et al Assessment of Lupus Anticoagulant Positivity in Patients With Coronavirus Disease 2019 (COVID-19). JAMA Netw Open. 2020;3(8):e2017539. August 12, 2020 PMID: 32785632 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2769229