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hepoxilin A3 (HxA3)

HxA3, a 12-lipoxygenase metabolite; induces hyperpolarization & inhibition of CA1 neurons & inhibits Ca+2-induced transmitter (NE) release.

Related

hepoxilin A3 [HxA3] receptor

General

12-lipoxygenase metabolite arachidonate; arachidonic acid [C20:4w6, ARA]

Properties

SIZE: MW = 304.5 G/MOL COMPARTMENT: membrane SECRETED-BY: platelet islet cell WITHIN: islets of Langerhans smooth muscle epithelial cell WITHIN: renal glomerulus

Database Correlations

PUBCHEM correlations

References

  1. Dho et al Biochem J 1990 Feb 15;266(1):63-8
  2. Pace-Asciak et al Biochem Biophys Res Commun 173:949 1990