Search
hepatitis B Surface antigen (HBsAg)
Clinical significance:
1) component of the outer viral envelope detectable in serum of most patients with acute & chronic hepatitis B infection
2) rises with HBeAg, but declines later
3) HBsAg indicates HBV infection, acute or chronic
4) with development of immunity, HBsAg disappears prior to disappearance of HBcAb IgM
5) conversion to HBsAg negative persists long-term in 95% [4]
Related
hepatitis B infection
hepatitis B surface antigen in serum (HBsAg)
hepatitis B virus (HBV)
hepatitis B virus (HBV) serology
Specific
Hepatitis B Surface Antigen Parenteral
General
hepatitis B Antigen
membrane protein
Properties
COMPARTMENT: cellular membrane
MOTIF: membrane region
References
- Manual of Medical Therapeutics, 28th ed, Ewald &
McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 369
- Laboratory Medicine: Test Selection & Interpretation.
Howanitz & Howanitz (eds), Churchill Livingstone, NY,
1991, pg 818-19
- Medical Knowledge Self Assessment Program (MKSAP) 14, 18.
American College of Physicians, Philadelphia 2006, 2018
- Alawad AS, Auh S, Suarez D, Ghany MG.
Durability of spontaneous and treatment-related loss of hepatitis
B s antigen.
Clin Gastroenterol Hepatol 2019 Jul 16
PMID: 31323381
https://www.cghjournal.org/article/S1542-3565(19)30751-7/pdf
Component-of
acellular pertussis vaccine/hepatitis b surface antigen/hepatitis b vaccine/poliovirus vaccine inactivated/tetanus toxoid
hepatitis serology chronic carrier panel