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hepatitis B E antigen (HBeAg)

Etiology: - hepatitis B infection, acute or chronic Clinical significance: 1) component of the hepatitis B Core antigen detected in serum when the virus is actively replicating 2) HBeAg indicates a stage of disease in which there is ongoing viral replication 3) HBeAg+ patients are more infective than HBsAg+ chronic hepatitis B carriers who are HBeAg- 4) HBeAg disappears during the acute phase of hepatitis B infection with development of immunity 5) HBeAg persists in chronic hepatitis B infection 5) hepatitis D virus (delta agent) suppresses hepatitis B virus (HBV) replication & eliminates HBeAg from serum

Related

hepatitis B e antigen in serum (HBeAg) hepatitis B infection hepatitis B virus (HBV) hepatitis B virus (HBV) serology

General

hepatitis B Antigen viral core protein

Properties


References

  1. Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 369
  2. Laboratory Medicine: Test Selection & Interpretation. Howanitz & Howanitz (eds), Churchill Livingstone, NY, 1991, pg 818-19
  3. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998

Component-of

hepatitis B Core antigen (HBcAg)