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hepatitis B carrier

Laboratory: - hepatitis B virus DNA in serum: positive, but low titer (< 10,000 IU/mL)* - serum ALT normal* - serum HBsAg positive - serum HBsAb negative - serum HBcIgM negative - serum HBcIgG positive - serum HBeAg negative - serum HBeAb variable * useful for survelliance of inactive carrier (every 6-12 months) Special laboratory: - survelliance for hepatocellular carcinoma in high-risk (high hepatitis B virus DNA) with abdominal ultrasound every 6 months [1]* * survelliance with serum alpha-fetoprotein insufficient [1] Management: - no treatment required [1]

Related

chronic hepatitis B

General

viral hepatitis carrier hepatitis B infection

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 16, 17, 18 American College of Physicians, Philadelphia 2012, 2015, 2018
  2. NEJM Knowledge+ Question of the Week. Dec 10, 2019 https://knowledgeplus.nejm.org/question-of-week/506/
  3. Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology 2009 Aug 29; 50:661 PMID: 19714720 Free full text
  4. European Association for the Study of the Liver. EASL 2017 clinical practice guidelines on the management of hepatitis B virus infection. J Hepatol 2017 Aug; 67:370 PMID: 28427875