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hepatic fibrosis

Pathology: - excessive accumulation of extracellular matrix proteins including collagen [1] Special laboratory: - vibration-controlled transient liver elastography may avoid biopsy [2] Complications: - advanced hepatic fibrosis results in cirrhosis Notes: - estimations of fibrosis from the fibrosis-4/5 score

Specific

cirrhosis

General

fibrosis liver disease

References

  1. Bataller R, Brenner DA Liver fibrosis. J Clin Invest. Feb 1, 2005; 115(2): 209-218 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546435/
  2. Medical Knowledge Self Assessment Program (MKSAP) 19. American College of Physicians, Philadelphia 2021