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heparin-platelet factor 4 antibody
Indications:
- evaluation of heparin-induced thrombocytopenia (HIT)
Clinical significance:
- sensitivity of 100%, specificity of 90% for (HIT)
- in association with the 4 Ts thrombocytopenia, time of thrombocytopenia, thrombosis, other causes for thrombosis accurately diagnoses HIT
Method:
- rapid (1-hour) agglutination test
Notes:
- no corresponding Loinc
- use heparin-associated platelet antibody
General
heparin-associated platelet antibody
References
- Linkins L-A et al.
Combination of 4Ts score and PF4/H-PaGIA for diagnosis and
management of heparin-induced thrombocytopenia: Prospective
cohort study.
Blood 2015 Apr 29;
PMID: 25926600
http://www.bloodjournal.org/content/early/2015/04/29/blood-2014-12-618165