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hemiplegic migraine

Familial & sporadic forms Eidemiology: - rare Clinical manifestations: - migraine - symptoms can last for hours to days, or rarely weeks - most resolve completely - aura (visual changes, numbness, paresthesias, dysarthria - fever - impaired consciousness, confusion to coma - ataxia - nausea/vomiting - phonophobia - hemiplegia Differential diagnosis: - TIA or stroke Management: - triptans & ergotamines are contraindicated because of vasoconstriction - NSAIDs - antiemetics - opiates - intranasal ketamine - prophylaxis - verapamil, acetazolamide, flunarizine, ketamine, lamotrigine naloxone have been used - amitriptyline, topiramate, & valproic acid may be beneficial for migraine with aura - beta-blockers generally avoided out of theoretical concern of ability of vessels to dilate

Specific

familial hemiplegic migraine

General

migraine headache hemiplegia (HP)

References

  1. American Migraine Foundation: Hemiplegic Migraine https://americanmigrainefoundation.org/resource-library/hemiplegic-migraine/
  2. IHS Classification ICHD-3 https://www.ichd-3.org/1-migraine/1-2-migraine-with-aura/1-2-3-hemiplegic-migraine/