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hematopoietic stem cell
Classification:
any one of several stages of stem cells including:
- pluripotential hematopoietic stem cells
- multipotential hematopoietic stem cells
- common myeloid progenitor (CFU-GEMM)
- common lymphoid progenitor
Physiology:
- human hematopoietic stem cells derive from endothelial cells but may be obtained in vitro from pluripotent stem cells [3] Phamacology:
- aryl hydrocarbon receptor antagonists (i.e. StemRegenin 1) promote the expansion of human hematopoietic stem cells [2]
Laboratory:
- hematopoietic progenitor cells in blood
Related
hematopoiesis
Specific
erythroid progenitor cell
megakaryoblast
monoblast
multipotential hematopoietic stem cell
myeloid stem cell
pleuripotential hematopoietic stem cell
promonocyte
General
blood cell
bone marrow cell
stem cell
References
- Henry's Clinical Diagnosis & Management by Laboratory Methods,
21st edition, McPherson RA & Pincus MR (es), W.B. Saunders Co.,
Philadelphia, PA. 2007. pg 485
- Boitano AE et al.
Aryl hydrocarbon receptor antagonists promote the expansion of
human hematopoietic stem cells.
Science 2010 Sep 10; 329:1345
PMID: 20688981
http://dx.doi.org/10.1126/science.1191536
- Sauvageau G and Humphries RK.
The blood stem cell Holy Grail?
Science 2010 Sep 10; 329:1291.
PMID: 20829472
http://dx.doi.org/10.1126/science.1195173
- Sugimura R et al.
Haematopoietic stem and progenitor cells from human
pluripotent stem cells.
Nature 2017 May 25; 545:432
PMID: 28514439
https://www.nature.com/nature/journal/v545/n7655/full/nature22370.html