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hemangiopericytoma
probably overlaps with solitary fibrous tumor, one time considered pericytic neoplasm.
Microscopic pathology:
- prominant thin walled branching vascular pattern, often staghorn configuration
- tumor cells closely packed,
- spindle shaped to round, uniform
- small amounts of cytoplasm, indistinct margins
- small bland vesicular nuclei
- cellular areas resembling solitary fibrous tumor
- differs from solitary fibrous tumor in lack of
- stromal hyalinization
- varying cellularity
- high mitotic rate
Immunohistochemistry:
- CD34 +
- CD99 +
- actin -
- desmin -
Clinical manifestations:
- slowly growing mass
Specific
hemangiopericytoma of meninges
General
intermediate grade fibroblastic/myofibroblastic neoplasm
References
- WHO Classification Tumours of Soft Tissue and Bone
Fletcher, Unni & Mertens Eds. IARC Press 2002
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