Search
HEAT repeat-containing protein 6 (amplified in breast cancer protein 1, HEATR6, ABC1)
Function: amplification-dependent oncogene
Structure: contains 4 HEAT repeats
Pathology:
- amplified in breast cancer cell lines MCF7 & BT474
General
HEAT repeat-containing protein (HEATR)
Properties
SIZE: entity length = 1181 aa
MW = 129 kD
MOTIF: HEAT repeat {159-198}
lysine-rich region {315-325}
MOTIF: lysine residue (SEVERAL)
glutamate-rich region {330-335}
MOTIF: glutamate residue (SEVERAL)
serine-rich region {383-390}
MOTIF: serine residue (SEVERAL)
HEAT repeat {452-490}
HEAT repeat {515-552}
HEAT repeat {558-595}
Database Correlations
UniProt Q6AI08
Pfam PF02985
Kegg hsa:6389
References
UniProt :accession Q6AI08