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hepatitis B surface antibody (HBsAb)
Etiology:
- exposure to hepatitis B virus with subsequent development of immunity
- successful hepatitis B vaccination
Clinical significance:
1) presence of HBsAb indicates immunity
2) rises with disappearance of HBcAg IgM with development of immunity
3) lags behind disappearance of HBsAg
4) does not appear in chronic hepatitis B
5) appears after successful hepatitis B vaccination
6) a quantitative value of > 10 mIU/mL implies immunity
Laboratory:
- hepatitis B surface antibody in body fluid
- hepatitis B surface antibody in serum
Related
hepatitis B infection
hepatitis B Surface antigen (HBsAg)
hepatitis B virus (HBV)
General
autoantibody
References
- Laboratory Medicine: Test Selection & Interpretation.
Howanitz & Howanitz (eds), Churchill Livingstone, NY,
1991, pg 818-19
- Medical Knowledge Self Assessment Program (MKSAP) 15,
American College of Physicians, Philadelphia 2009
- Hepatitis B Surface Antibody
Laboratory Test Directory ARUP: 20090
- Panel of 5 tests
Laboratory Test Directory ARUP: 20454
Component-of
hepatitis B core Ab + surface Ab + surface Ag
obstetric panel
obstetric panel HIV