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N-acylneuraminate-9-phosphatase (neu5Ac-9-Pase, Haloacid dehalogenase-like hydrolase domain-containing protein 4) (NANP C20orf147 HDHD4)

Function: - carbohydrate metabolism; aminosugar metabolism N-acylneuraminate 9-phosphate + H2O N-acylneuraminate + phosphate Cofactor: Mg+2 Inhibition: - inhibited by vanadate & Ca+2 Kinetic parameters: - KM=0.09 mM for N-acetylneuraminate 9-P - Vmax=112 umol/min/mg enzyme with N-acetylneuraminate 9-P as substrate Structure: - belongs to the haloacid dehalogenase-like hydrolase superfamily, NANP family

General

phosphomonoesterase

Properties

SIZE: MW = 28 kD entity length = 248 aa MOTIF: active site

Database Correlations

UniProt Q8TBE9 Pfam PF00702 ENZYME 3.1.3.29

References

UniProt :accession Q8TBE9