hairy & enhancer of split (HES)

Many if not all are transcriptional repressors

Specific

hairy/enhancer-of-split related with YRPW motif 1 (hairy & enhancer of split-related protein 1, HESR-1, cardiovascular helix-loop-helix factor 2, HES-related repressor protein 2, HERP2, HEY1, CHF2, HESR1) hairy/enhancer-of-split related with YRPW motif 2 (cardiovascular helix-loop-helix factor 1, hairy & enhancer of split-related protein 2, HESR-2, hairy-related transcription factor 2, HES-related repressor protein 2, protein gridlock homolog, HEY2, CHF1, GRL, HERP, HERP1, HRT2) hairy/enhancer-of-split related with YRPW motif-like protein (hHeyL, hairy-related transcription factor 3, hHRT3, HEYL HRT3) transcription cofactor HES-6 (hairy & enhancer of split 6, C-HAIRY1, HES6) transcription factor HES-2 (hairy & enhancer of split 2, HES2) transcription factor HES-3 (hairy & enhancer of split 3) transcription factor HES-4 (hairy & enhancer of split 4, bHLH factor Hes4, HES4) transcription factor HES-5 (Hairy & enhancer of split 5, HES5) transcription factor HES-7 (hairy & enhancer of split 7, bHLH factor Hes7, HES7)

General

DNA-binding protein transcription factor (TF)

Properties

COMPARTMENT: cell nucleus MOTIF: DNA-binding motif helix-loop-helix NAME: helix-loop-helix FOR-BINDING-VIA: helix-loop-helix Orange

References

UniProt :accession Q9HCC6, Q96HZ4