glutamate receptor delta-2 subunit; GluR delta-2 (GRID2 GLURD2)

Function: - post-synaptic receptor for excitatory neurotransmitter L-glutamate - interacts with AIP1, AP4M1, BECN1, GOPC, GRID2IP, SHANK1 & SHANK2 (putative) Structure: - the PDZ-binding motif mediates interaction with GOPC (By similarity) - belongs to the glutamate-gated ion channel (TC 1.A.10) family Compartment: - cell membrane - cell junction, synapse, postsynaptic cell membrane

General

glutamate receptor delta glycoprotein

Properties

SIZE: entity length = 1007 aa MW = 113 kD COMPARTMENT: plasma membrane MOTIF: exoplasmic domain {24-566} MOTIF: signal sequence {1-23} N-glycosylation site {N293} N-glycosylation site {N426} transmembrane domain {567-587} cytoplasmic loop {588-635} transmembrane domain {636-656} exoplasmic loop {657-830} transmembrane domain {831-851} cytoplasmic domain {852-1007} MOTIF: AP4M1 interaction {921-991} PDZ recognition motif NAME: PDZ recognition motif SITE: 1005-1007 FOR-BINDING-VIA: PDZ domain

Database Correlations

OMIM 602368 UniProt O43424 PFAM correlations

References

UniProt :accession O43424