granuloma formation (GO:0002432)

The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents The center of a granuloma consists of fused macrophages which can become necrotic. Notes: - This term was added by GO_REF:0000022.

References

gene ontology: GO:0002432