probable G-protein coupled receptor 1 (GPR1)

Function: - orphan receptor - probable opioid receptor Structure: belongs to the G-protein coupled receptor 1 family Compartment: cell membrane Expression: expressed in hippocampus Pathology: can act as a co-receptor for HIV-1

General

glycoprotein G-protein coupled receptor; serpentine receptor

Properties

SIZE: entity length = 355 aa MW = 41 kD COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-41} MOTIF: N-glycosylation site {N14} transmembrane domain {42-62} cytoplasmic loop {63-73} transmembrane domain {74-94} exoplasmic loop {95-112} MOTIF: cysteine residue {C110} MODIFICATION: cysteine residue {C187} transmembrane domain {113-133} cytoplasmic loop {134-154} transmembrane domain {155-175} exoplasmic loop {176-210} MOTIF: cysteine residue {C187} MODIFICATION: cysteine residue {C110} transmembrane domain {211-231} cytoplasmic loop {232-247} transmembrane domain {248-268} exoplasmic loop {269-286} transmembrane domain {287-307} cytoplasmic domain {308-355}

Database Correlations

OMIM 600239 UniProt P46091 Pfam PF00001 Entrez Gene 2825 Kegg hsa:2825

References

UniProt :accession P46091