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golgi
A stacked array of membranous cisternae & connecting tubules or vesicles between the nucleus & the secretory pole of a cell. It is receives nascent polypeptides from the endoplasmic reticulum, destined for the secretory pathway.
Function:
3 major functions: [2]
1) carbohydrate processing & modification of proteins & lipids moving through the secretory pathway
2) protein sorting & transport, receiving membrane from the ER & delivering it to the plasma membrane or other intracellular sites
3) membrane scaffold onto which diverse signaling, sorting & cytoskeleton proteins adhere
Classification:
- cis, trans & intermediate GOLGI compartments have been described
Related
Golgi, Camillo
Specific
acrosome
cis-Golgi
trans-Golgi (trans-Golgi network, TGN)
General
organelle
References
- Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999.
- Altan-Bonnet N, Sougrat R, Lippincott-Schwartz J.
Molecular basis for Golgi maintenance and biogenesis.
Curr Opin Cell Biol. 2004 Aug;16(4):364-72. Review.
PMID: 15261668
- de Graffenried CL, Bertozzi CR.
The roles of enzyme localisation and complex formation in
glycan assembly within the Golgi apparatus.
Curr Opin Cell Biol. 2004 Aug;16(4):356-63. Review.
PMID: 15261667
- Colanzi A, Suetterlin C, Malhotra V.
Cell-cycle-specific Golgi fragmentation: how and why?
Curr Opin Cell Biol. 2003 Aug;15(4):462-7. Review.
PMID: 12892787
- Barr FA, Short B.
Golgins in the structure and dynamics of the Golgi apparatus.
Curr Opin Cell Biol. 2003 Aug;15(4):405-13. Review.
PMID: 12892780
- Bankaitis VA, Morris AJ.
Lipids and the exocytotic machinery of eukaryotic cells.
Curr Opin Cell Biol. 2003 Aug;15(4):389-95. Review.
PMID: 12892778
- Ponnambalam S, Baldwin SA.
Constitutive protein secretion from the trans-Golgi network
to the plasma membrane.
Mol Membr Biol. 2003 Apr-Jun;20(2):129-39. Review.
PMID: 12851070
- Rabouille C, Jokitalo E.
Golgi apparatus partitioning during cell division.
Mol Membr Biol. 2003 Apr-Jun;20(2):117-27. Review.
PMID: 12851069
- Machamer CE.
Golgi disassembly in apoptosis: cause or effect?
Trends Cell Biol. 2003 Jun;13(6):279-81. Review.
PMID: 12791290