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golgi

A stacked array of membranous cisternae & connecting tubules or vesicles between the nucleus & the secretory pole of a cell. It is receives nascent polypeptides from the endoplasmic reticulum, destined for the secretory pathway. Function: 3 major functions: [2] 1) carbohydrate processing & modification of proteins & lipids moving through the secretory pathway 2) protein sorting & transport, receiving membrane from the ER & delivering it to the plasma membrane or other intracellular sites 3) membrane scaffold onto which diverse signaling, sorting & cytoskeleton proteins adhere Classification: - cis, trans & intermediate GOLGI compartments have been described

Related

Golgi, Camillo

Specific

acrosome cis-Golgi trans-Golgi (trans-Golgi network, TGN)

General

organelle

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999.
  2. Altan-Bonnet N, Sougrat R, Lippincott-Schwartz J. Molecular basis for Golgi maintenance and biogenesis. Curr Opin Cell Biol. 2004 Aug;16(4):364-72. Review. PMID: 15261668
  3. de Graffenried CL, Bertozzi CR. The roles of enzyme localisation and complex formation in glycan assembly within the Golgi apparatus. Curr Opin Cell Biol. 2004 Aug;16(4):356-63. Review. PMID: 15261667
  4. Colanzi A, Suetterlin C, Malhotra V. Cell-cycle-specific Golgi fragmentation: how and why? Curr Opin Cell Biol. 2003 Aug;15(4):462-7. Review. PMID: 12892787
  5. Barr FA, Short B. Golgins in the structure and dynamics of the Golgi apparatus. Curr Opin Cell Biol. 2003 Aug;15(4):405-13. Review. PMID: 12892780
  6. Bankaitis VA, Morris AJ. Lipids and the exocytotic machinery of eukaryotic cells. Curr Opin Cell Biol. 2003 Aug;15(4):389-95. Review. PMID: 12892778
  7. Ponnambalam S, Baldwin SA. Constitutive protein secretion from the trans-Golgi network to the plasma membrane. Mol Membr Biol. 2003 Apr-Jun;20(2):129-39. Review. PMID: 12851070
  8. Rabouille C, Jokitalo E. Golgi apparatus partitioning during cell division. Mol Membr Biol. 2003 Apr-Jun;20(2):117-27. Review. PMID: 12851069
  9. Machamer CE. Golgi disassembly in apoptosis: cause or effect? Trends Cell Biol. 2003 Jun;13(6):279-81. Review. PMID: 12791290