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Gq-alpha family (GNAQ)
Activates PLC beta-1.
Related
Gq-protein
Specific
G14-alpha (guanine nucleotide-binding protein alpha-14 subunit, G-protein alpha subunit 14, GNA14)
G15-alpha (guanine nucleotide-binding protein alpha-15 subunit, G alpha-15, G alpha-16, G16-alpha, GNA15, GNA16)
GTP-binding regulatory protein Gy alpha (guanine nucleotide binding protein Gy alpha, heterotrimeric G-protein Gy alpha, GNA11)
guanine nucleotide-binding protein Gq subunit alpha (guanine nucleotide-binding protein alpha-q, GNAQ, GAQ)
General
G-alpha
Properties
SIZE: MW = 41-52 kD
COMPARTMENT: plasma membrane*
CELL: most cell types*
ORGANISM: eukaryote*
MOTIF: binding site
FOR-BINDING-OF: G-beta/gamma
P-loop
EFFECTOR-BOUND: guanosine triphosphate
Mg+2-binding site
References
- Simon et al,
Diversity of G proteins in signal transduction.
Science 252:802 1991
PMID: 1902986