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glycogen storage disease type 0 (muscle, liver types)

Genetics: - associated with defects in GYS1 (muscle), GYS2 (liver) Clinical manifestations: - fasting hypoglycemia presenting in infancy or early childhood - although feeding relieves symptoms, it often results in postprandial hyperglycemia & hyperlactatemia Laboratory: - fasting hypoglycemia - high serum ketones - low serum alanine & serum lactate

General

glycogen storage disease (glycogenosis)

References

UniProt :accession P13807