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glomerulonephropathy; glomerulopathy
Etiology:
1) glomerulonephritis
2) diabetic nephropathy
3) amyloidosis
4) drug-induced glomerular injury [5]
5) minimal change disease
6) thin glomerular basement membrane disease
7) obesity-related glomerulonepropathy
Differential diagnosis:
- minimal change disease
- nephrotic syndrome, children. Rx with prednisone
- focal segmental glomerulosclerosis
- nephrotic syndrome
- obesity, premature birth, blacks
- Rx with weight reduction, ACE inhibitor, mycophenolate, rituximab
- thin glomerular basement membrane disease (hematuria Rx with ACE inhibitor)
- membranous glomerulonephritis
- nephrotic syndrome, whites, elderly. Rx after trial of spontaneous recovery
Interactions
disease interactions
Specific
diabetic nephropathy; diabetic glomerulosclerosis; Kimmelstiel-Wilson disease (DMN)
glomerulonephritis (GN, nephritic syndrome)
minimal change disease; minimal change glomerulonephropathy (MCD)
nephrotic syndrome
obesity-related glomerulonephropathy
thin glomerular basement membrane disease; benign familial hematuria
General
nephropathy
References
- Manual of Medical Therapeutics, 28th ed, Ewald &
McKenzie (eds), Little, Brown & Co, Boston, 1995
- Medical Knowledge Self Assessment Program (MKSAP) 11, 17, 18.
American College of Physicians, Philadelphia 1998, 2015, 2018.
- Hogan J, Mohan P, Appel GB.
Diagnostic tests and treatment options in glomerular disease: 2014 update.
Am J Kidney Dis. 2014 Apr;63(4):656-66. Review.
PMID: 24239051
- Glassock RJ.
An update on glomerular disease in the elderly.
Clin Geriatr Med. 2013 Aug;29(3):579-91. Review.
PMID: 23849009
- Markowitz GS, Bomback AS, Perazella MA.
Drug-induced glomerular disease: direct cellular injury.
Clin J Am Soc Nephrol 2015 Jul 7; 10:1291
PMID: 25862776 Free PMC Article
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Glomerular Diseases
https://www.niddk.nih.gov/health-information/kidney-disease/glomerular-diseases