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glyoxalase domain-containing protein 4 (GLOD4, C17orf25, CGI-150, My027)
Function: interacts with NUDT9
Structure: belongs to the glyoxalase 1 family
Compartment: mitochondria (probable)
Alternative splicing: named isoforms=3
Expression:
- expressed in heart, brain, liver, kidney, pancreas & placenta
- not expressed in skeletal muscle & lung
Pathology:
- expression is decreased in hepatocellular carcinoma compared to adjacent non-cancerous liver tissue
- transfection in hepatocellular carcinoma cells & overexpression can inhibit the cell growth
General
mitochondrial protein
Properties
SIZE: MW = 35 kD
entity length = 313 aa
COMPARTMENT: mitochondria
Database Correlations
UniProt Q9HC38
Pfam PF00903
References
UniProt :accession Q9HC38