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gepant
Indications:
- treatment of migraine attack [1]
Dosage:
- oral [1]
Pharmacokinetics:
- gepants able to cross the blood brain barrier
Adverse effects:
- appear to be minimal [1]
Mechanism of action:
- CGRP receptor antagonist
- gepants do not cause vasoconstriction
Related
calcitonin gene-related peptide (CGRP)
Specific
atogepant (Qulipta)
rimegepant (Nurtec ODT)
ubrogepant (Ubrelvy)
General
calcitonin gene-related peptide (CGRP) inhibitor
References
- George J.
Oral CGRP Inhibitor Helps Relieve Migraine Attack
About 20% report being pain-free within 2 hours.
MedPage Today. April 26, 2018
https://www.medpagetoday.com/meetingcoverage/aan/72559