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hemoglobin gamma chain

Function: - component of hemoglobin F together with alpha globin Expression: erythrocytes Pathology: - some gamma variants can cause severe jaundice & cyanosis in premature & new born babies - component of hemoglobin Portland?

Related

gamma globin gene

Specific

hemoglobin gamma-1 chain hemoglobin gamma-2 chain (HBG2)

General

globin chain

Properties

MOTIF: heme-binding site COFACTOR-BOUND: heme{FE+2} FOR-BINDING-OF: O2

References

  1. Locus Link (HBG1) :accession 3047
  2. Locus Link (HBG2) :accession 3048
  3. Hbvar; Human hemoglobin variants http://globin.cse.psu.edu/globin/html/huisman/variants/

Component-of

hemoglobin-variant