gamma-chain disease

Encountered most often in the elderly. Resembles a malignant lymphoma rather than multiple myeleoma. Manifestations consist of lymphadenopathy, anemia, fever, & often hepatosplenomegaly. Lytic bone lesions are not present. The disease course is variable, from death in a few months to several years.

Properties

PREVALENCE: EXTREMELY-RARE

References

Cotran et al Robbins Pathologic Basis of Disease, W.B. Saunders Co, Philadelphia, PA 1989 pg 744