Search
galactose intolerance
inability to absorb galactose often is not exclusively associated with inability to absorb glucose
Epidemiology: rare
Genetics:
- autosomal recessive
- chromosome 22 defect
Clinical manifestations:
- generally presents in first weeks of life
- severe diarrhea, leading to dehydration
- bloating
- excess gas production
- vomiting
- weight loss
- symptoms occur when fed breast milk or standard infant formula
Laboratory:
- electrolytes: low serum bicarbonate (metabolic acidosis)
- genetic testing
Complications:
- nephrolithiasis
Management:
- fructose-based formulas that do not contain glucose or galactose
- affected children often tolerate glucose & galactose as they get older
Related
galactose
galactosemia
General
carbohydrate inborn error of metabolism
References
- Glucose and galactose malabsorption / intolerance;
Galactosemia
http://www.foodintolerances.com.au/food-intolerances-glucose-galactose.aspx