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gamma-aminobutyric acid receptor subunit rho-3 (GABA(A) receptor subunit rho-3, GABRR3)
Function:
- GABA-A receptor subuniut
- forms a ternary complex with SQSTM1 & PRKCZ (putative)
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment:
- cell junction, synapse, postsynaptic cell membrane
General
glycoprotein
membrane protein
protein subunit
Properties
SIZE: entity length = 467 aa
MW = 54 kD
MOTIF: signal sequence {1-23}
exoplasmic domain {24-266}
MOTIF: cysteine residue {C184}
MODIFICATION: cysteine residue {C198}
cysteine residue {C198}
MODIFICATION: cysteine residue {C184}
N-glycosylation site {N220}
transmembrane domain {267-287}
cytoplasmic loop {288-299}
transmembrane domain {300-320}
exoplasmic loop {321-331}
transmembrane domain {332-352}
SQSTM1 interaction {347-448}
MOTIF: cytoplasmic loop {353-446}
transmembrane domain {447-467}
Database Correlations
UniProt A8MPY1
PFAM correlations
References
UniProt :accession A8MPY1
Component-of
GABA-A receptor