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gamma-aminobutyric acid receptor subunit rho-3 (GABA(A) receptor subunit rho-3, GABRR3)

Function: - GABA-A receptor subuniut - forms a ternary complex with SQSTM1 & PRKCZ (putative) Structure: - belongs to the ligand-gated ionic channel (TC 1.A.9) family Compartment: - cell junction, synapse, postsynaptic cell membrane

General

glycoprotein membrane protein protein subunit

Properties

SIZE: entity length = 467 aa MW = 54 kD MOTIF: signal sequence {1-23} exoplasmic domain {24-266} MOTIF: cysteine residue {C184} MODIFICATION: cysteine residue {C198} cysteine residue {C198} MODIFICATION: cysteine residue {C184} N-glycosylation site {N220} transmembrane domain {267-287} cytoplasmic loop {288-299} transmembrane domain {300-320} exoplasmic loop {321-331} transmembrane domain {332-352} SQSTM1 interaction {347-448} MOTIF: cytoplasmic loop {353-446} transmembrane domain {447-467}

Database Correlations

UniProt A8MPY1 PFAM correlations

References

UniProt :accession A8MPY1

Component-of

GABA-A receptor