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gamma-aminobutyric acid receptor subunit rho-2; GABA(A) receptor subunit rho-2 (GABRR2)
Function:
- GABA-A receptor subunit
- Rho-2 GABA receptor could play a role in retinal neurotransmission
- interacts with SQSTM1 (putative)
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment:
- cell junction, synapse, postsynaptic cell membrane
General
gamma-aminobutyric acid (GABA) A receptor, rho
transmembrane 4e protein
Properties
SIZE: entity length = 465 aa
MW = 54 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-261}
MOTIF: signal sequence {1-20}
N-glycosylation site {N120}
cysteine residue {C178}
MODIFICATION: cysteine residue {C192}
cysteine residue {C192}
MODIFICATION: cysteine residue {C178}
N-glycosylation site {N254}
transmembrane domain {262-285}
cytoplasmic loop {286-288}
transmembrane domain {289-311}
exoplasmic loop {312-322}
transmembrane domain {323-345}
cytoplasmic loop {346-443}
transmembrane domain {444-465}
exoplasmic domain {465-465}
Database Correlations
OMIM 137162
UniProt P28476
PFAM correlations
Entrez Gene 2570
Kegg hsa:2570
References
UniProt :accession P28476